Glycoside hydrolase family 101

Endo-alpha-N-acetylgalactosaminidase
Identifiers
Symbol Glyco_hydro_101
Pfam PF12905
Pfam clan CL0058
CAZy GH101
Glycosyl hydrolases related to GH101 family
Identifiers
Symbol GHL
Pfam PF11308
Pfam clan CL0058
CAZy GH101

In molecular biology, glycoside hydrolase family 101 is a family of glycoside hydrolases.

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,[4] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. [5]

Glycoside hydrolase family 101 CAZY GH_101 includes enzymes with endo-α-N-acetylgalactosaminidase EC 3.2.1. activity and can be split into several subfamilies.[6][7]

References

  1. ^ Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=41477. 
  2. ^ Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779. 
  3. ^ Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.
  4. ^ Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.
  5. ^ CAZypedia, an online encyclopedia of carbohydrate-active enzymes.
  6. ^ Willis LM, Zhang R, Reid A, Withers SG, Wakarchuk WW (2009). "Mechanistic investigation of the endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae R6.". Biochemistry 48 (43): 10334–41. doi:10.1021/bi9013825. PMC 2953539. PMID 19788271. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2953539. 
  7. ^ Naumoff DG (2010). "GH101 family of glycoside hydrolases: subfamily structure and evolutionary connections with other families.". J Bioinform Comput Biol 8 (3): 437–51. PMID 20556855. http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20556855.